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2.1 The group of patients before treatment, 36 cases of bronchial tuberculosis cases with pulmonary atelectasis in 10 cases, 21 patients had chest X-ray showed pulmonary lesions. Bronchoscopy findings: edema in 14 cases (38.9%), necrotizing ulcers in 10 cases (27.8%), 12 cases of proliferative granulation (33.3%).
2.2 Efficacy of intensive stage clinical control of clinical symptoms at the end of 30 cases (83.3%) were cured, 6 patients (16.7%), sputum conversion in 28 cases (77.8%); 9 months after clinical control of clinical symptoms of 36 cases (100% ), sputum conversion in 32 cases (88.9%); September atelectasis after the cure rate was 100% (10/10); chest lesions treatment efficiency (significant absorption + absorption) was 85.7% (18/21).
2.3 Comparison of the fiberoptic group of cases reviewed 6 to 12 times (average 10) are more satisfied with local therapy. Strengthening the end stage of recovery of bronchial disease: markedly effective in 11 cases (30.6%), effective in 16 cases (44.4%), unchanged in 8 cases (22.2%), deteriorated in 1 case (2.8%), overall response (markedly effective + effective) 27 cases, 75.0% of the total valid.
2.4 The case of adverse reactions in this group of drug infusion in the treatment of bronchial washing and during the 3 cases of chest tightness, shortness of breath, after symptomatic treatment remission. All the cases were not found in liver and kidney dysfunction.
2.5 1 year followed up by long-term efficacy, clinical symptoms were no recurrence of clinical control,[link widoczny dla zalogowanych], sputum conversion were no re-yang. Because of deterioration in 1 patient during the lumen is too narrow to be caused by surgery, the remaining cases, scar tissue lesion stability, no further luminal narrowing.

1 Materials and Methods paper to write

Clinical data were 1.1 cases of our hospital selected patients with endobronchial tuberculosis, cough symptoms after 2 weeks lavage, pathological, or acid-fast bacilli diagnosed as bronchial tuberculosis, diagnosis Chinese Medicine will be the development of TB diagnostic criteria for credits [1]. In 36 patients, 20 males and 16 females, aged 18 to 77 years, average 46.3 years old. 19 cases mainly dry cough,[link widoczny dla zalogowanych], cough, sticky fluid in 9 cases sputum, cough, bloody sputum in 8 cases.
1.2 The inspection methods used in Japan PENTAX EB-1570K electronic bronchoscope examination. Premedication and anesthesia according to routine, the nose into the mirror, turn on the glottis, trachea, carina, bronchi on both sides of one level above sub-section observation, found that lesions that biopsy and / or submit brush biopsy and bacteriology.
1.3 Methods 3HRZE/6HRE drug treatment program. Drugs, code-named H: isoniazid, 0.4 / time, 1 time / d. R: rifampin, 0.6 / time, 1 time / d. E: ethambutol, 0.4 / time, 1 time / d. Z: Pyrazinamide, 0.75 / time, 2 times / d.
1.4 Observation items
1.4.1 Strengthening clinical stage 2 times a week asking cough, sputum and wheezing conditions 1 week consolidation phase asked cough, sputum and wheezing situation.
1.4.2 Check the strengthening phase of sputum acid-fast bacilli sputum smears for 3 month and 1 sputum culture, the consolidation phase every 3 months 3 consecutive sputum smear.
1.4.3 bronchoscopy examination in all cases before and after treatment compared 1 year after treatment, every 3 months later to track 1.
1.4.4 Other tests X-ray enhancement phase 1 per month, the consolidation phase 1 every 3 months. Stage before treatment and strengthen the chest CT examination at the end of the 1. Monthly testing of liver and kidney function.
1.5 Clinical criteria to determine clinical medicine in accordance with Ministry of Health Council to develop a determine the efficacy of standard reference 1982 revised national tuberculosis prevention and control of the meeting of the ≥ 1 / 2 as effective, lesion uptake <1 / 2 is not changed for the worse lesions increased.
Statistical Methods Statistical Methods 1.6 SPSS10.0 statistical package for data analysis, count data are used χ2 test.


2 results

3 Discussion
36 cases with persistent bronchial cough for the performance evaluation of tuberculosis treatment in bronchoscopy



Abstract Objective To observe the bronchoscope for the performance of stubborn cough bronchial tuberculosis treatment. Methods 36 patients with intractable cough bronchial tuberculosis hospital for the performance of drug treatment in patients before and after treatment were performed bronchoscopy. Results after 9 months of clinical symptoms, sputum conversion rate of pulmonary atelectasis were 100% cure rate, 85.7% of chest lesions, lesions of bronchial bronchoscopy review the total 75.0%, good effect. Conclusion The evaluation of endobronchial tuberculosis by bronchoscopy therapy is an effective way, with safety, fewer complications, patients with the advantages of easy to accept.
Key words stubborn cough; bronchial tuberculosis; bronchoscopy; therapy
Analysis of therapeutic effect of 36 endobronchial tuberculosis for chronic cough bybronchoscopy
LV Pei-jin, CAO Zi-yang, WANG Li-qin.The Second People's Hospital affiliated to Taishan Medical Universityof Liaocheng, Linqing 252600, China
【Abstract】 Objective To analysis of therapeutic effect of endobronchial tuberculosis for chronic cough bybronchoscopy.Methods 36 inpatients with endobronchial tuberculosis were treated with drug-infusing therapy.All cases were exiamed bybronchoscopybefore and after treatment.Results After 9 months of treatmemt, the clinical manifestation , the sputum negative conversion rate and the pulmonary atelectasis cure rate were 100%. The improvement rate by X-ray was 85.7% and 75.0% bybronchoscopy.Conclusion To analysis of therapeutic effect of endobronchial tuberculosis bybronchoscopy is an effectivemethod, and it has many merits , such as safe, low complication, easy to accept.
【Key words】
Chronic cough; Endobronchial tuberculosis; Bronchoscopy; Therapeutic effect
According to a recent national epidemiological survey result, tuberculosis is still is the most serious infectious diseases. Bronchial tuberculosis (TBTB) is the common type of tuberculosis to stenosis or obstruction involved segmental bronchi as the main feature. Cough is a common respiratory disease symptoms, most patients the clinical diagnosis easier to clear, a small number of patients showed persistent cough, diagnosis unknown, and often requires the use of bronchoscopy to confirm the diagnosis. This paper summarizes the past 5 years in our hospital 36 patients with intractable cough in patients with the results of bronchoscopy, and bronchoscopy before and after treatment results were compared, the report is as follows.

Endobronchial tuberculosis, also known as bronchial tuberculosis, occurs in the bronchial mucosa or submucosa of the TB change,[link widoczny dla zalogowanych], is a common and the incidence of tuberculosis,[link widoczny dla zalogowanych], tuberculosis patients accounted for about 10% to 60% [4]. Epidemiological data show that about 550 million in China by Mycobacterium tuberculosis infection, tuberculosis prevalence rate of 367/10 million, indicating that TB is a common infectious disease in China, but also focus on the control of one of the major diseases [5]. Jun Zhuang together [6] reported 3375 cases of bronchoscopy in the diagnosis of 105 cases of bronchial tuberculosis, the positive rate was 3.1%, indicating that bronchial tuberculosis is more common respiratory diseases.
Slow onset of bronchial tuberculosis, the symptoms varied, the lack of specificity, and 2.6% to 24% of patients asymptomatic. The group of 36 patients with bronchial tuberculosis clinical manifestations of cough, sputum, fever, hemoptysis. As cough, sputum symptoms are prominent, obvious symptoms of poisoning tuberculosis, bronchial tuberculosis, lack of typical symptoms of TB most often misdiagnosed as pneumonia, bronchitis, these conditions have led to misdiagnosis and missed diagnosis of bronchial tuberculosis.
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